Scanomed - Nukleráis medicina központok

Bone metastasis

Bone metastases can develop in case of several tumorous diseases, during the course of which imbalance develops between osteoclasts and osteoblasts due to the effect of biochemical factors produced by cancer cells. Due to this fact, regenerative ability of the bone decreases, the bone becomes weak, cracks and this may result in metastatic bone fractures and complaints.

Bone metastases are in most cases a result of breast, prostate or lung cancers, and from tumorous diseases of the hemopoetic system primarily multiple myeloma affects bones also.
Bone metastases may remain symptomless for a long period of time.
Symptoms of bone metastasis are: radiating bone pain and weakening bones due to the cancer process that may crack or fracture without any special impact or accident.
Detection of bone metastatic processes in most cases is performed with bone scintigraphy, SPECT-CT, or in several cases with FDG PET-CT.


Sm-153 bone pain-palliation