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Neuroendocrine tumors

These are tumors which produce hormone-like substances. It is frequent that neuroendocrine tumors not constantly produce hormones triggering the clinical symptoms, but they empty the produced and stored substances suddenly into the bloodstream in a big amount thus causing seizure-like, not rarely life-threatening malaise for patients.

The hormone production is not, or only barely regulated thus the tumor secretes much more hormones than it is necessary for the body, mainly the following: serotonin, arginine vasopressin, insulin (hormone that decreases blood sugar level), parathormone-related peptide (PTH-RP, hormone that increases calcium level), gastrin (hormone that increases gastric-acid secretion), ACTH (adrenocorticotrop hormone that stimulates the adrenal gland).

Symptoms may vary depending on the produced hormones and the location of the tumor. Treatment: depending on the stage of the disease it may be surgery, chemotherapy or radiation therapy.

 

DIAGNOSTIC PROCEDURES:

I-123-MIBG SPECT-CT

In111/Tc99m-Octreotide SPECT-CT

I-131 MIBG SPECT-CT

In case of fail of the above mentioned, if it they are poorly differentiated tumors a complementary FDG PET-CT may be reasonable in some cases.

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